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How Africa-led clinical trials are shaping vaccine science

For decades, Africa's role in HIV research was framed as that of a peripheral "host, not driver". The just-concluded 2025 International Aids Society (IAS) conference in Kigali made it unmistakably clear: that era is over. African scientists are now designing clinical trials, steering analysis and defining the questions that matter. Africa is not just at the table; it is building it.

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